Clinical Pipeline

Nexalis Therapeutics has a diversified pipeline of three drug candidates at various stages of clinical development, supported by a total funding facility of $64.6 million.

3
Drug Candidates
2
Therapeutic Areas
2
Modalities (Oral & Inhaled)

Our Drug Delivery Platforms

Nexalis Therapeutics leverages two distinct drug delivery modalities to develop innovative therapies for patients with significant unmet medical needs.

Oral Delivery

Next-Generation Oral Formulations

Our oral drug delivery platform focuses on developing novel formulations that enhance the therapeutic profile of established compounds. SRX-25 combines esketamine with a CYP-450 inhibitor to enable home-use administration for treatment-resistant depression.

  • Potential for home-use administration
  • FDA 505(b)(2) regulatory pathway
Learn about SRX-25 →
Inhaled Delivery

Precision Inhaled Drug-Device

Our proprietary inhaled drug-device combination platform enables rapid-onset delivery of therapeutics directly to the systemic circulation, ideal for conditions requiring immediate relief.

  • Rapid onset of action (within minutes)
  • Precise dosing via proprietary device
Inhaled Phase 2 Ready

IRX-211

Breakthrough Cancer Pain (BTcP)

Inhaled drug-device combination for rapid-onset relief of Breakthrough Cancer Pain.

Learn More
Inhaled Phase 1 Ready

IRX-616a

Panic Disorder

Inhaled drug-device combination for rapid intervention in Panic Disorder episodes.

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Oral Phase 1 Planning

SRX-25

Treatment-Resistant Depression (TRD)

Oral esketamine formulation for Treatment-Resistant Depression with potential for home-use administration.

Learn More

Pipeline Overview

Our Development Approach

Nexalis Therapeutics focuses on de-risking drug development by leveraging established compounds with known safety profiles. Our programs utilize the FDA 505(b)(2) regulatory pathway where applicable, accelerating development timelines by building on existing safety and efficacy data.

With a total funding facility of $64.6 million from Linlithgow Family Office, we are well-positioned to advance our clinical programs and deliver transformative therapies to patients with significant unmet medical needs.

$64.6M
Total Facility